In an enthralling documentary, Dan Snow and archaeologist Raksha Dave delve into the catastrophic impact of the Black Death on Britain 700 years ago, a pandemic that extinguished around half of the population, or three million people. The duo embarks on a journey to trace the origins and merciless spread of the plague, starting from its arrival on Britain's South coast in June 1348, through the bustling trade routes that brought the disease to Melcombe Regis, Dorset. Their investigation takes them to various hotspots of the outbreak, including the Old Operating Theatre in London and Wildwood Animal Sanctuary in Kent, where they explore the role of rats in dispersing the bubonic plague. Through dramatic reconstructions and visits to places like Nottingham University's biomedical laboratories, they uncover the rapid spread and deadly impact of the plague, offering a month-by-month account of how it ravaged the country, decimating cities, towns, and villages alike.
The documentary not only showcases the horrific symptoms and desperate attempts at cures through brutal medical practices of the time but also leverages cutting-edge research to explain why the Black Death remains the deadliest pandemic in history. The personal stories of victims, from princes to paupers, are brought to light, revealing the indiscriminate nature of the disease. Dan's visit to Canterbury Cathedral and Raksha's investigation into the recent discovery of mass graves beneath a tranquil London square underline the widespread desperation and devastation. Their journey through the history of the Black Death, culminating in the discovery of its indiscriminate toll and the unveiling of mass graves in London, not only sheds light on the darkest chapters of British history but also ignites a profound understanding of the tragedy, making a compelling case for why this documentary is a must-watch for anyone interested in the profound impacts of pandemics on human society.

A third of the population regularly struggle with our sleep, which rose to one in two during the pandemic - the highest it's ever been. However, as more and more people seek help, an explosion in sleep science is enabling the study of sleep in ways not possible before. What's more, recent breakthroughs are uncovering what's happening in our brains and bodies while we're asleep, getting us closer than ever to understanding the importance of sleep for our health. Michael Mosley shows why cutting our sleep short can be linked to a host of illnesses, including serious diseases like Alzheimer's.
Revealing the very latest science breakthroughs and packed with personal anecdotes, this programme is a useful guide to anyone looking for tips and insights on how to get the benefits from learning how to sleep well.

Follow three women at risk of developing Alzheimer’s and join a groundbreaking study to try to prevent the disease, while sharing their ups and downs, anxiously watching for symptoms, and hoping they can make a difference. Barb, Sigrid, and Karen all had mothers with Alzheimer’s and witnessed first hand the devastation wrought by the disease, not only on the mind and body, but on patients’ families.

Magic mushrooms, long considered sacred by the Indigenous Mazatec in Mexico, become the subject of scientific studies measuring the intense effects of its Psilocybin and its potential therapeutic use.
In the second episode, we are introduced to Ben, who’s battled with crippling Obsessive-Compulsive Disorder (OCD) his entire life. When he had his firstborn, Ben’s life became full of panic attacks regarding his son’s safety, and he knew something had to change. Ben signed up for a psilocybin-assisted therapy clinical trial which was testing whether the psychedelic could help people with severe OCD. In the session under the influence of psilocybin, Ben felt decomposed and eventually grew into a tree. While living as a tree, he saw his human self, playing with his child. Though this sounds scary, from Ben’s perspective, it was beautiful. He was one with the universe, seeing himself in the ultimate third-person perspective. Finally, he saw how it could be different if he didn’t let his OCD control him. And several months out, all the symptoms disappeared.
Ben’s story is one of many told in this series, which gives hope that help is right around the corner for the millions who suffer —often in silence— with debilitating mental disorders. But Michael Pollan’s work is showcasing the success stories. Often, even in the most successful trials, psychedelic-assisted therapy only helps up to a third of people enter remission. More frequently, patients are helped —sometimes substantially— but they still suffer with their illnesses and some people aren’t helped at all.

To maximize longevity, you might think it’s best to play it safe and stay cozy. But some scientists believe we should do the opposite, as exposure to extreme temperatures can trigger our bodies’ own defenses against the killer diseases of old age. Chris heads for the freezing Arctic with his brothers Liam and Luke to take on the ultimate cold therapy.

A ground-breaking new trial at Imperial College London sees, for the first time ever under controlled conditions, a psychedelic drug tested head-to-head against a standard antidepressant as a treatment for depression. The film follows a pioneering team of scientists and psychotherapists as they compare the effects of psilocybin (the active ingredient of magic mushrooms) with an antidepressant on a small group of participants with clinical depression.
This is scientific research at its most cutting edge. With over seven million people being prescribed antidepressants each year in England alone, this drug trial is an important milestone in understanding a completely different treatment for depression. How do psychedelic drugs measure up against the industry-standard antidepressants that have been popular since the 1990s? The empirical results of the trial are explored alongside the participants’ powerful lived experience.