Wood travels through war-torn Afghanistan, crossing the Oxus River into Central Asia and the Silk Road city of Samarkand where, in a drunken brawl, Alexander killed the friend who had previously saved his life.

In 335 BC Alexander of Macedonia set off on an expedition to conqueror the world. The voyage of Alexander the Great covered more than 22,000 miles in ten years, from Greece to India and back, through some of the most difficult and unforgiving terrain. Michael Wood was hot on his trail, following, as closely as possible, in the footsteps of Alexander and the army that he drove to achieve the impossible. In this programme: the Lebanese city of Tyre, scene of Alexander's most desperate battle; the Palestinian legend of `Two-Horned Alexander'; and the Egyptian oasis of Siwa, where Alexander was proclaimed pharaoh and son of God.

Michael crosses Iran towards the Caspian Sea. He meets nomads who tell of Alexander's tryst with an Amazon queen, and the living descendants of Alexander's Persian enemies, who have their own tales of `Alexander the Accursed'.

The final leg takes him from the Khyber Pass through Pakistan to the Punjab, where Alexander's army mutinied and he was forced to return across the Makran Desert to Babylon, where he died at only 32 years of age.