This highly anticipated psychedelic docuseries showcases what these substances teaches people about consciousness, dying, addiction, depression and transcendence. Filmmaker Alex Gibney and best-selling author Michael Pollan present it in four parts, each focused on a different mind-altering substance: LSD, psilocybin, MDMA, and mescaline. With Pollan as our guide, we journey to the frontiers of the new psychedelic renaissance -- and look back at almost-forgotten historical context -- to explore the potential of these substances to heal and change minds as well as culture.
The first chapter is a great introduction to the topic of LSD, from its 1943 origins to today's microdosing trend, for those who don’t already know a lot about the subject, and a fun and entertaining refresher on LSD for even experts in the field. The show takes us on a journey through the history of the powerful compound, from its discovery and its early medical use, to secret CIA mind-control studies, the counterculture and its banning, and finally to our current renaissance. It includes amazing clips of LSD’s inventor Albert Hofmann and powerful personal testimonies of individuals who have healed their suffering through LSD.

Jacoba Ballard was an only child, conceived via donor sperm, who always dreamed of having a brother or sister. When an at-home DNA test led her to the discovery of not one but seven half-siblings, she realized that she had stumbled across a major finding.
Jacoba discovers a shocking scheme involving a former Indianapolis based fertility doctor, who, in a case of fertility fraud, used his own sperm to impregnate dozens of unsuspecting patients.

Follow three women at risk of developing Alzheimer’s and join a groundbreaking study to try to prevent the disease, while sharing their ups and downs, anxiously watching for symptoms, and hoping they can make a difference. Barb, Sigrid, and Karen all had mothers with Alzheimer’s and witnessed first hand the devastation wrought by the disease, not only on the mind and body, but on patients’ families.

Follow the dramatic personal journey of Hugh Herr, a biophysicist working to create brain-controlled robotic limbs. At age 17, Herr’s legs were amputated after a climbing accident. Frustrated by the crude prosthetic limbs he was given, Herr set out to remedy their design, leading him to a career as an inventor of innovative prosthetic devices.
Now, Herr is teaming up with an injured climber and a surgeon at a leading Boston hospital to test a new approach to surgical amputation that allows prosthetic limbs to move and feel like the real thing. Herr’s journey is a powerful tale of innovation and the inspiring story of a personal tragedy transformed into a life-long quest to help others.

A huge social experiment is underway. Fifty-five million Americans say they currently use cannabis, and that number is expected to grow as voters push for legalization in more and more states. The film investigates the story of cannabis from the criminalization that has disproportionately harmed communities of color to the latest medical understanding of the plant.
What risks does cannabis pose to the developing brain? How much do we know about its potential medical benefits? As cannabis becomes socially accepted, scientists are exploring its long-term health consequences.

The Last Shaman James is an all American boy whose promising life is brought to a halt by acute depression. Turning his back on the most progressive western treatments and medicines, James discovers ayahuasca in search of healing in the Peruvian jungle. Over the course of 10 months venturing from Shaman to Shaman, James finds friendship, answers and a kind of redemption hidden deep in the Peruvian amazon. (Click CC for subtitles)