At an extraordinary moment in the history of one of the world’s oldest and most controversial drugs, Dr Javid Abdelmoneim investigates the very latest medical and scientific research into the effects of cannabis on the brain and the body, to find out whether it will help or harm patients.
Javid meets the young epilepsy patient responsible for changing the law around medicinal cannabis in the UK and sees the remarkable effects it has on his condition. He visits a medicinal cannabis farm in Denmark to learn how a company known for growing the recreational drug are now producing medicinal cannabis to be exported all over Europe. He travels to Israel, to find out why they have been using cannabis as a medicine for over 20 years and meets the scientists studying the safety and effectiveness of cannabis in treating pain. And he meets the so-called godfather of cannabis, who at 88 years old is still an active research scientist and considered the world’s leading cannabis expert.

Gaby Roslin and Amir Khan present a program in which they apply the latest science to some of the worst sleepers. They include an extreme snorer, a man who suffers from night terrors, a woman who has restless leg syndrome, and a man with chronic insomnia for 20 years.
The film also shows a sleep deprivation experiment to test for risky behaviour, pain resistance and emotional control. When the subjects reach the final hours of the challenge, the experiment begins to take its toll as the participants' emotions go into overdrive, with one threatening to quit altogether.

Someday, I will die. But should I? If I was offered a longer life, I would take that in a second. But how long is too long? Is death something I should deny forever, or is death and the role it plays in the universe something I am better off accepting?

The final episode of this series looks at what happens to the brain when someone uses psychedelic drugs. It looks at how psychedelic drugs may be useful in dealing with anxiety in cancer survivors and serious depression. It explores the history of psychedelics and examines early medical experimentation with the drug. It also discussed why psychedelics were banned and examines how they affect the brain.

Modern headlines are claiming mindfulness may cure anxiety, depression, and a whole host of other health problems. How can this simple practice of watching your own breath change the way your brain works? And can that change your life? The fourth episode of the series looks at the power of mindfulness and meditation. It examines different kinds on meditation (transcendental, dynamic, and religious) and notes that they are different from mindfulness meditation (Satipatthana). Also it talks to neuroscientists who discuss what happens in the brain during meditation.

The film is a descriptive time-lapse journey about the magical, mysterious and medicinal world of fungi and their power to heal, sustain an contribute to the regeneration of life on Earth that began 3.5 billion years ago.
Imagine an organism that feeds you, heals you, reveals secrets of the universe and could help save the planet. You'll see it through the eyes of mycologists, like renowned Paul Stamets, about the unlimited potential of fungi in the fields of food, medicine, expanding consciousness, bioremediation, neurogenesis and treating end-of-life anxiety.