Everyone from the most simple-minded to the deepest thinking has pondered a question that strikes at the core of our existence: Is there life after death? What happens to the soul after we die? People who have had near-death experiences claim to have visited the other side before getting yanked back into consciousness. Now, some of the brightest minds in science are trying to understand how life can persist beyond the physical and what will it look like. It might be a quantum state based on the fundamental laws of the universe. Ultimately, it is a journey that struggles to decode the most complicated instrument in the universe: the human brain.

Professor Marcus du Sautoy goes in search of answers to one of science's greatest mysteries: how do we know who we are? While the thoughts that make us feel as though we know ourselves are easy to experience, they are notoriously difficult to explain. He has his mind scrambled by a cutting-edge experiment in anaesthesia. After, Marcus is given an out-of-body experience in a bid to locate his true self.