Beginning with the origins of the universe in the Big Bang, Sagan describes the formation of different types of galaxies and anomalies such as galactic collisions and quasars. The episodes moves further into ideas about the structure of the Universe, such as different dimensions (in the imaginary Flatland and four-dimensional hypercubes), an infinite vs. a finite universe, and the idea of an oscillating Universe (similar to that in Hindu cosmology). The search into other ideas such as dark matter and the multiverse is shown, using tools such as the Very Large Array in New Mexico. Cosmos Update shows new information about the odd, irregular surfaces of galaxies and the Milky Way perhaps being a barred spiral galaxy

Legendary oceanographer and TED prize winner Dr. Sylvia Earle is on a mission to save our oceans. Mission Blue is part action-adventure, part expose of an Eco-disaster. More than 100 scientists, philanthropists and activists gather in the Galapagos Islands to help fulfill Dr. Earle's lifelong wish: build a global network of marine protected areas, like underwater national parks, to protect the natural systems that keep humans alive.
As the expedition ends, the Deep water Horizon oil well explodes. With oil gushing into the Gulf of Mexico, Sylvia and an environmental dream team race around the world trying to defend her 'Hope Spots'.