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A Winning Design clarifies what makes a mammal different from reptiles and birds. No, it isn't egg-laying: both the platypus and the echidna are egg-laying mammals; it's their ability to adapt. And it's this adaptability that becomes the crux of the remainder of the series. From the tiniest bat to the massive blue whale, all mammals share the ability to nurture their young on milk and regulate their own temperatures.

Sagan discusses the story of the Heike crab and artificial selection of crabs resembling samurai warriors, as an opening into a larger discussion of evolution through natural selection (and the pitfalls of intelligent design). Among the topics are the development of life on the Cosmic Calendar and the Cambrian explosion; the function of DNA in growth; genetic replication, repairs, and mutation; the common biochemistry of terrestrial organisms; the creation of the molecules of life in the Miller-Urey experiment; and speculation on alien life (such as life in Jupiter's clouds). In the Cosmos Update ten years later, Sagan remarks on RNA also controlling chemical reactions and reproducing itself and the different roles of comets (potentially carrying organic molecules or causing the Cretaceous–Paleogene extinction event).

The idea of intelligence is explored in the concepts of computers (using bits as their basic units of information), whales (in their songs and their disruptions by human activities), DNA, the human brain (the evolution of the brain stem, frontal lobes, neurons, cerebral hemispheres, and corpus callosum under the Triune Brain Model), and man-made structures for collective intelligence (cities, libraries, books, computers, and satellites). The episode ends with speculation on alien intelligence and the information conveyed on the Voyager Golden Record.

Caesar has been murdered, Mark Antony emerges from the Senate in shock, only to face Quintus Pompey and his thugs, who immediately follow him to try to kill him. Brutus returns home shaking after the murder. His mother is already plotting the return of the Roman Republic. Titus Pullo asks Eirene to marry him and she accepts. Erastes Fulmen kidnaps Lucius Vorenus' children and sister-in-law.
Mark Antony proposes an amnesty to the rest of the senate to keep the peace and allow the Republic to continue. Vorenus says goodbye to Niobe while Rome says goodbye to Caesar. Vorenus and Pullo track down Fulmen to a bath house, where he tells them he killed Vorenus' family.

There is a battle playing out inside your body right now. It started billions of years ago and it is still being fought in every one of us every minute of every day. This is the story of a viral infection - the battle for the cell.
This film reveals the exquisite machinery of the human cell system from within the inner world of the cell itself - from the frenetic membrane surface that acts as a security system for everything passing in and out of the cell, the dynamic highways that transport cargo across the cell and the remarkable turbines that power the whole cellular world to the amazing nucleus housing DNA and the construction of thousands of different proteins all with unique tasks. The virus intends to commandeer this system to one selfish end: to make more viruses. And they will stop at nothing to achieve their goal. Exploring the very latest ideas about the evolution of life on earth and the bio-chemical processes at the heart of every one of us, and revealing a world smaller than it is possible to comprehend, in a story large enough to fill the biggest imaginations.

In 1994, a thirteen year old boy disappeared from San Antonio, Texas. Three and a half years later, he is found alive and well thousands of miles away in a village in southern Spain with a story of kidnapping and torture. His family is overjoyed to bring him home. But all is not quite as it seems.
The boy bears many of the same distinguishing marks he always had, but why does he now have a strange accent? Why does he look so different? Any why doesn't the family seem to notice these glaring inconsistencies? It's only when an investigator starts asking questions that this strange tale takes an even stranger turn.