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Of all the wonders of the human body, there's one more mysterious than any other. Blood: five precious litres that keep us alive. Yet how much do we really know about this sticky red substance and its mysterious, life-giving force? Michael Mosley gives up a fifth of his own blood to perform six bold experiments". From starving it of oxygen to injecting it with snake venom, Michael reveals the extraordinary abilities of blood to adapt and keep us alive. Using specialist photography, the programme reveals the beauty in a single drop. Michael even discovers how it tastes when, in a television first, he prepares a black pudding with his own blood. Down the ages, our understanding of blood has been as much myth as science, but Michael reveals there might be truth in the old vampire legends, as he meets one of the scientists behind the latest research that shows young blood might be able to reverse the ageing process - the holy grail of modern medicine.

For centuries scientists have been attempting to come up with an elixir of youth. Now remarkable discoveries are suggesting that ageing is something flexible that can ultimately be manipulated. The scientists are attempting to piece together why we age and more vitally for all of us, what we can do to prevent it. But which theory will prevail? Does the real key to controlling how we age lie with a five-year-old boy with an extraordinary ageing disease or with a self-experimenting Harvard professor? Could one of these breakthroughs really see our lives extend past 120 years?

This episode explores what can give brains a boost. In America, Angela tries out a new treatment that's proven to help memory and concentration. In Japan, a remarkable 100-year-old reveals the colourful foods that keep minds more active. Plus Chris discovers the best exercise we can do for our brains. At the cutting-edge of science, discover how injections of young people's blood may help beat dementia.

Death is life's greatest certainty. But that may be about to change. Scientists have discovered an immortal animal that may hold the secret of endless regeneration. They're on the brink of editing our DNA so that we can cure ageing like a disease. Or is dying necessary for the survival of our species?

To maximize longevity, you might think it’s best to play it safe and stay cozy. But some scientists believe we should do the opposite, as exposure to extreme temperatures can trigger our bodies’ own defenses against the killer diseases of old age. Chris heads for the freezing Arctic with his brothers Liam and Luke to take on the ultimate cold therapy.

Chris turns to longevity doctor Peter Attia to find out how changing his eating habits can help his quest for longevity. Ironically, the answer is to eat no food at all for four long days. If he can bear the hunger, fasting will unlock his body’s own anti-aging powers and give Chris the edge he needs when he tries to hunt for his next meal … by spearfishing off the Great Barrier Reef.