The story begins with Tyson sitting at a campfire, and telling how the wolf changed through artificial selection, and selective breeding into the dog breeds around today. He then enters the Ship of Imagination, and explains natural selection with the process that helped to create the polar bears. Along the way he talks about DNA, genes and mutation. Next he goes to a forest and describes the Tree of life, this leads him to discussing the evolution of the eye. He then discusses extinction, by going to a monument called the Halls of Extinction, dedicated to the broken branches of the tree of life. Explaining the five great Extinction events. He then tells how some life has survived, and then focuses on the tardigrade. From there he talks about what other kinds of life might have been created on other worlds. He then goes to Saturn's moon Titan. From there he speculates about life and how it first began. He then returns to Earth and tells about abiogenesis and how life changed and evolved. The show ends with an animated sequence from the original series of life's evolution from one cell to humans.

As the early June sun begins to set over a calm river in Central Hungary, masses of ghostly shapes emerge from their larval cases to take to the air for the first time. They are mayflies and in a spectacular display, thousands of them demonstrate how the very first wings were used. From the stunning aerobatics of hoverflies in an English garden to the mass migration of purple crow butterflies in the valleys of Taiwan, this episode tells the tale of the first animals ever to take to the air. Unique footage reveals the lightning fast reactions of bluebottles and hoverflies, filmed with one of the world's fastest cameras, and Sir David Attenborough handles the world's largest (and perhaps most ferocious) insect - the Titan beetle.

The world of invertebrates exists in a web of relationships with plants and other animals. Unique footage of the world's smallest insect (a fairy wasp only quarter of a millimetre long) shows it flying underwater to find the eggs of water beetles in which to lay its own brood. Some ants 'farm' the trees that give them shelter, creating areas known as 'Devil's gardens'. To make sure these grow without competition, they kill off other seedlings in the surrounding vegetation. The blister beetle's larvae huddle together on the end of a piece of grass and mimic a female bee. When a male bee tries to mate with the 'female', the larvae grab on to his belly. Confused, he flies away and searches for a real female. When he eventually finds her and mates with her, the beetle larvae hurriedly swap from his front on to her back, and hence get carried back to her nest where they eat her pollen supplies.

Invertebrates don't always operate alone. True society was the last feature to evolve in invertebrates, as recently as the time of Tyrannosaurus. In the last programme see the tensions below the surface in some of the great social structures built by insects, and witness the carnage when an ant colony and a termite colony wage war.

The idea of intelligence is explored in the concepts of computers (using bits as their basic units of information), whales (in their songs and their disruptions by human activities), DNA, the human brain (the evolution of the brain stem, frontal lobes, neurons, cerebral hemispheres, and corpus callosum under the Triune Brain Model), and man-made structures for collective intelligence (cities, libraries, books, computers, and satellites). The episode ends with speculation on alien intelligence and the information conveyed on the Voyager Golden Record.

Sex is the key to the immortality of genes, and any tactic necessary will be deployed in the cause of reproduction - even if it's suicidal to the participant. This episode explores many of the most ingenious, complex, and dramatic methods that animals employ to ensure the continuation of their genetic line.