Ltes follow the development of some the biggest names in Rock in the 70s and 80s, among them Queen, Bruce Springsteen & The E Street Band, The Police and Dire Straits and shows how, through events such as Live Aid and the rise of MTV, rock achieved a global influence on culture and politics. The film concludes in the early 90s, as U2 effectively brought the era to a close by reinventing the big rock show.

British Indie music was once seen as the bastion of the over earnest 'High Fidelity' snob who would sneer at chart success. the indie label was the redoubt against the forces of mediocrity and was a precious source of integrity and honesty. A generation would find meaning in the music of The Smiths, the archetypal indie group of the 1980's. From the Stone Roses, the heir manque of the indie music crown, via Suede’s dark sexuality and the media saturation of Brit-pop's Blur v Oasis, indie was now a marketing device, ultimately losing any of it's once cherished intimacy and integrity

In the 80s the nature of the Latino Diaspora changes again. From Cuba a second wave of refugees to United States – the Mariel exodus – floods Miami . The same decade sees the sudden arrival of hundreds of thousands of Central Americans (Salvadorans, Guatemalans, and Nicaraguans) fleeing death squads and mass murders at home like activist, Carlos Vaquerano. By the early 1990s, a political debate over illegal immigration – has begun. Globalization, empowered by NAFTA, means that as U.S. manufacturers move south, Mexican workers head north in record numbers. A backlash ensues: tightened borders, anti-bilingualism, state laws to declare all illegal immigrants felons. But a sea change is underway: the coalescence of a new phenomenon called Latino American culture-as Latinos spread geographically and make their mark in music, sports, politics, business, and education.

Series concludes with the focus shifting to the United States in the post-war years of the 1950s and beyond. Beginning with arguably the most notorious work of 20th century classical music, John Cage's 'silent' composition 4'33", it looks at how a series of maverick Americans re-invented the sound of classical music into a more simple form, bringing back harmonies and rhythms that made it increasingly popular with audiences across the world. It also examines how this music found its way into a spiritual realm, with the strain of pared-down religious composition that came to be known as 'holy minimalism'. From the Maverick concert hall in Woodstock, New York to an Orthodox cathedral in Estonia to a car park in Peckham, south London, the story is told by a stellar line-up of contributors including Philip Glass, Steve Reich, John Adams, Arvo Pärt and John Tavener.

The tour was designed by Willie Williams, who has worked on every U2 tour since 1982. Williams had been toying with ideas for 360-degree stadium staging for U2 for a number of years, and presented sketches of a four-legged design to the group near the end of their Vertigo Tour in 2006. The inspiration for the 'spaceship-on-four-legs' design, nicknamed 'the Claw', came from the landmark Theme Building at Los Angeles International Airport.

The 25 October 2009 concert in Pasadena, California was streamed live on U2's YouTube channel, the first time a concert was streamed live on YouTube. Over 10 million viewers streamed the concert, making it the largest streaming event in the website's history. The shoot was directed by Tom Krueger, who had previously worked with the band on the film U2 3D.