This scientific detective tale tells the story of a remarkable group of pioneers who wanted to reach the ultimate extreme: absolute zero, a place so cold that the physical world as we know it doesn't exist, electricity flows without resistance, fluids defy gravity and the speed of light can be reduced to 38 miles per hour. Absolute zero became the Holy Grail of temperature physicists and is considered the gateway to many new technologies, such as nano-construction, neurological networks and quantum computing. The possibilities, it seems, are limitless. The first episode Chronicles the major discoveries leading towards the mastery of cold, beginning with King James I's court magician, Cornelius Drebbel, who managed to air condition the largest interior space in the British Isles in 1620. Other stories will include the first "natural philosopher," Robert Boyle, a founder of the Royal Society in Great Britain; the Grand Duke Ferdinand II de Medici's involvement in the creation of the first thermometer; the establishment of the laws of thermodynamics by three young scientists, Sadi Carnot, James Joule and William Thomson; and Michael Faraday's critical achievement in liquefying several other gases which set the stage for the commercial application of cold to refrigeration and air conditioning.

Professor of physics Jim Al-Khalili investigates the most accurate and yet perplexing scientific theory ever - quantum physics, the perplexing theory of sub-atomic particles. Turning his attention to the world of nature, can quantum mechanics explain the greatest mysteries in biology? The European robin navigates using one of the most bizarre effects in physics - quantum entanglement, a process which seems to defy common sense. Jim finds that even the most personal of human experiences - our sense of smell - is touched by ethereal quantum vibrations. According to new experiments it seems that our quantum noses are listening to smells. Jim discovers that the most famous law of quantum physics - the uncertainty principle - is obeyed by plants and trees as they capture sunlight during the vital process of photosynthesis. Jim wonders if the strange laws of the sub-atomic world, which allow objects to tunnel through impassable barriers in defiance of common sense, could effect the mechanism by which living species evolve?

For one night only, Professor Brian Cox goes unplugged in a specially recorded programme from the lecture theatre of the Royal Institution of Great Britain. In his own inimitable style, Brian takes an audience of famous faces, scientists and members of the public on a journey through some of the most challenging concepts in physics. With the help of Jonathan Ross, Simon Pegg, Sarah Millican and James May, Brian shows how diamonds - the hardest material in nature - are made up of nothingness; how things can be in an infinite number of places at once; why everything we see or touch in the universe exists; and how a diamond in the heart of London is in communication with the largest diamond in the cosmos.

Stephen Hawking is the most famous scientist on the planet. But behind the public face lies an argument that has been raging for almost 30 years. Has he been wrong for the last 30 years? Hawking shot to fame in the world of physics when he provided a mathematical proof for the Big Bang theory. This theory showed that the entire universe exploded from a singularity, an infinitely small point with infinite density and infinite gravity. Hawking was able to come to his proof using mathematical techniques that had been developed by Roger Penrose. These techniques were however developed to deal not with the beginning of the Universe but with black holes". Science had long predicted that if a sufficiently large star collapsed at the end of its life, all the matter left in the star would be crushed into an infinitely small point with infinite gravity and infinite density – a singularity. Hawking realised that the Universe was, in effect, a black hole in reverse. Instead of matter being crushed into a singularity, the Universe began when a singularity expanded to form everything we see around us today, from stars to planets to people. Hawking realised that to come to a complete understanding of the Universe he would have to unravel the mysteries of the black hole and its paradoxes

Comedian Ben Miller returns to his roots as a physicist to try to answer a deceptively simple question: what is one degree of temperature? His quest takes him to the frontiers of current science as he meets researchers working on the hottest and coldest temperatures in the universe, and to a lab where he experiences some of the strangest effects of quantum physics - a place where super-cooled liquids simply pass through solid glass. Plus, Ben installs his very own Met office weather station at home. Ben's investigations in this personal and passionate film highlight the importance of measurement and accuracy in the 21st century.

The black hole at the centre of the Milky Way is getting ready to feast. A gas cloud three times the size of our planet has strayed within the gravitational reach of our nearest supermassive black hole. And across the globe, telescopes are being trained on the heart of our Milky Way galaxy, some 27,000 light years from Earth, in the expectation of observing this unique cosmic spectacle. For cosmic detectives across the Earth, it is a unique opportunity. For the first time in the history of science, they hope to observe in action the awesome spectacle of a feeding supermassive black hole.