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This episode discusses the human exploration of Antarctica, in particular the mission led by Captain Robert Falcon Scott, whose team died on the way back from the South Pole. It shows the scientific work in the modern human bases in Antarctica, especially Mawson Base and its observation of Adelie Penguins (partially through tracking devices). The second half of the episode describes how the series was made. Most crucial was of course the camera work. To get access to the wildlife of the sea, for example, boats, divers, suspended capsules and remotely controlled cameras mounted on inflatables were used. Particularly dangerous to divers were Leopard Seals and other predators. The film concludes that although working in Antarctica is now much easier than during the early days of exploration, human footsteps on the continent are still exceedingly rare in part because of international treaties prohibiting industrial exploitation.

Are the wealthy just born in the right place at the right time? Are the poor victims of a system designed to keep them down? Or do physics and biology determine who is rich and who is poor? Throughout history, distribution of wealth is governed by hidden forces: DNA, environmental stress, patterns of human migration and even the laws of thermodynamics! Nature seems to demand winners and losers in life. But does this mean greed is king, and the rich can take what they want? Or is cooperation – between microorganisms, monkeys, and humans – more essential to survival of a species?

It is a nightmare that has stalked us for centuries: hordes of human beings transformed into mindless, cannibalistic monsters. Could this civilization-ending nightmare become reality? Scientists have discovered pathogens that turn insects into the walking dead. New strains of viruses are attacking humans every day. Mathematicians have calculated the likelihood of surviving a zombie virus outbreak: they’re not hopeful. Now neuroscientists are discovering how easy it is for us to lose conscious control of our bodies. Are we at risk of becoming puppets? If we were in the middle of a zombie apocalypse, would we even know it?

Humanity’s potential seems limitless. But could we become as powerful as God? Scientific breakthroughs grant our species seemingly divine abilities. Biologists tinkering with DNA are figuring out ways to grow new life forms, while neuroscientists try to create artificial consciousness. Statisticians around the world are using big data to predict the future and computer scientists have discovered a "God algorithm" that could solve any global problem in an instant. But to truly become God, we not only have to be all knowing, but all being. Quantum physicists are figuring out how to teleport matter at the speed of light!

In the final challenge of the game of life, raising offspring is the ultimate prize. Continuing the line through the next generation, is the next best thing to immortality. But it’s far from easy... Some parents must risk their own lives for their offspring.

Brian travels across the US and encounters some astonishing creatures that reveal how the senses evolved. It is a story that takes him through life's journey, from single-celled organisms to sentient beings.