Dr Janina Ramirez shows how medieval manuscripts gave power to the king and united the kingdom in an age of plague, warfare and rebellion, discovers that Edward III used the manuscripts he read as a boy to prepare him for his great victory at the battle of Crecy and reveals how a vigorous new national identity bloomed during the 100 Years War with France. In the British Library's Royal Manuscripts collection Dr Ramirez finds out that magnificent manuscripts like the Bedford Hours, taken as war booty from the French royal family, were adapted for the education of English princes. She also explores how knowledge spread through a new form of book - the encyclopaedia.

The story of the British Library's Royal Manuscripts collection reaches its end with the last great flowering of illumination, in the magnificent courts of the Tudors. Dr Janina Ramirez investigates astrological texts created for Henry VII, and unwraps his will - still in its original, extravagantly-decorated velvet and gold cover. She hears music written for Henry VIII, which went unperformed for centuries; and reads love notes between the king and Anne Boleyn, written in the margins of a prayer book. Nina also visits Bruges, the source of many of the greatest manuscripts, where this medieval art form collided with the artistic innovations of the Renaissance.

April 1453. Sultan Mehmed II unleashes an artillery attack on Constantinople unlike any the world has ever known. It's the largest concentration of cannons that the world had seen in one place. The monumental task of keeping the Ottomans out of Constantinople falls on the shoulders of Genoese soldier of fortune Giovanni Giustiniani. He and his men must defend 14 miles of city walls. Mehmed launches his ambitious plans to break through the walls of Constantinople, but Giustiniani's mercenaries manage to forestall the attacks.

Mehmed II sends his elite troops into the teeth of Emperor Constantine's defenses along the city's ancient stone walls. The defenders, led by Italian soldier-of-fortune Giovanni Giustiniani, repel every attack. Mehmed's men dig underground tunnels in an attempt to shatter city walls. The tides turn against the Ottomans when a naval blockade founders.

It's this moment where now both sides realize that no quarter will be asked, and no quarter will be given. Surrender is no longer even an option. You're in this to the end. You either die or you triumph, and there is no other alternative. Amid a spiral of brutality and low morale, Mehmed makes Giustiniani an enticing offer. The grand vizier urges Mehmed to seek a truce with his rival.

Hours before Mehmed II launches his final assault, an ominous sight shakes both sides. Rumors of a 40-ship fleet's imminent arrival have swirled for weeks, but it's exact whereabouts remained unknown. Ottoman cannons reduced the city walls to rubble, and Venetian reinforcements arrived too late. The conquest of Constantinople ushers in a new era for the Ottoman Empire, being a dominant force in world politics for 300 years. Mehmed II, in many senses, changed the nature of world history.